Targeting FGFR pathway in human hepatocellular carcinoma (HCC) expressing pFGFR and pMET for anti-tumor activity
نویسندگان
چکیده
Innovative Cancer Research, ASAN Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea Department of Oncology, Asan Medical Center, Seoul, Republic of Korea Department of Pathology, Asan Medical Center, Seoul, Republic of Korea Department of Radiation Oncology, Asan Medical Center, Seoul, Republic of Korea Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. Department of Life Sciences, Sookmyung Women’s University, Seoul, Republic of Korea These authors contributed equally to this work.
منابع مشابه
Targeting FGFR Pathway in Human Hepatocellular Carcinoma: Expressing pFGFR and pMET for Antitumor Activity.
The MET receptor tyrosine kinase, the receptor for hepatocyte growth factor (HGF), has been implicated in cancer growth, invasion, migration, angiogenesis, and metastasis in a broad variety of human cancers, including human hepatocellular carcinoma (HCC). Recently, MET was suggested to be a potential target for the personalized treatment of HCC with an active HGF-MET signaling pathway. However,...
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